《使命召唤4》与所有系列前作相比将发生显著的变化，首当其冲的就是游戏时代背景的改变。由前几部的以第二次世界大战时期为中心，直接转变为以现代战争为背景。但现在还不清楚游戏是以真实的现代战争为题材，还是选择类似于虚构的国际冲突为主题，也有传言说本作将选取与EA公司的《战地》系列相类似的“中东战争”为题材。在游戏的技术进步方面，该消息来源透露，利用强大的次世代技术，《使命召唤 4》的逼真程度将远超乎玩家们的想象。举例来说，在系列的前几代里，玩家在瞄准敌人头部射击后最多也就只有3、4种结果，但在《使命召唤4》中，将至少有 16种以上的不同的表现效果。子弹可以把敌人的钢盔击飞、甚至打得在头上转圈，子弹击中头部后的效果也将视其命中部位不同产生相应的变化。毋庸质疑的是，《使命召唤》系列向来重视单机游戏部分的体验，而跨入次世代后，多人联机游戏的地位开始变得越发重要起来。该消息来源透露，《使命召唤4》将支持最多54 名玩家同时在线游戏，这无疑意味着前所未有的大规模多人游戏新体验。
As the video game strategy guide market has evolved, so has BradyGames. After 10 years in the business, BradyGames knows what gamers – both casual and hardcore – want and need in a strategy guide. It's about developing the most comprehensive guides for the games that pose numerous challenges.
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Each guide – from the collectible Signature Series to the standard video and PC books – features in-depth content, detailed screen captures and quick reference and strategy tips. This, plus unique formats and products, allows us to help gamers get the most out of their games.